Laparoscopic technology as a new and progressive technology continues to be used in various areas of general surgery. Because of its wide field of vision, magnification effect, clearer local anatomy, and 3-5 abdominal poke holes to solve the problem, laparoscopic technology is rapidly applied to gastroduodenal perforation repair. The etiology of gastroduodenal perforation is mostly chronic gastric ulcer, partly perforated by gastric cancer, mostly induced by overeating, alcoholism, staying up late, anxiety and mental tension. Gastroduodenal perforation is mostly caused by the sudden appearance of epigastric pain, due to the stimulation of stomach acid and food into the abdominal cavity, the sharp appearance of total abdominal pain, the appearance of total abdominal pressure and rebound pain, abdominal rectus muscle plate changes, abdominal pain is difficult to tolerate, mostly fever and vomiting and other manifestations. Gastroduodenal perforation mostly has the manifestation of acute peritonitis and will be rapidly admitted to the hospital for treatment. Before surgery, routine blood tests, liver and kidney functions, electrolytes, blood glucose, lipids, coagulation, infectious disease tests, electrocardiogram, digital photography of the chest and abdomen, and in some patients, abdominal CT will be performed to clarify the cause of the disease, combined with the presence of combined medical diseases for related tests. Once the diagnosis of gastroduodenal perforation is made, a gastric tube will be placed for gastrointestinal decompression and drainage of gastric acid and gastric contents to reduce the etiology of abdominal infection. After gastroduodenal perforation, gastric acid enters the peritoneal cavity leading to chemical peritonitis, and there is a large amount of peritoneal exudate, resulting in insufficient effective circulating blood, which requires intravenous fluids to replenish the volume, and more than 6-8 hours usually combined with abdominal bacterial infection, which requires antibiotic anti-inflammatory treatment. The treatment of gastroduodenal perforation mostly adopts gastroduodenal perforation repair. Duodenal perforation is mostly benign disease, and gastric perforation may be gastric cancer perforation, so gastric perforation should take tissue biopsy at the gastric perforation to exclude gastric cancer. Traditional gastroduodenal perforation repair is mostly a 12cm long wound in the upper abdomen, or even longer, which is more traumatic. Laparoscopic gastroduodenal perforation repair mostly takes a 3-hole method into the abdominal cavity, which can integrate diagnosis and treatment into one, and can explore the whole abdominal cavity for hepatobiliary, gastroduodenal, small intestine and large intestine, pelvic organs, and flush and drain the whole abdominal cavity, and after the operation, flush and drain extensively in the abdominal cavity, and leave a drain in the hepatogastric space. A drainage tube is placed in the hepatogastric space. Since laparoscopic gastroduodenal perforation repair is a relatively technically simple procedure, it is easy to be negligent in postoperative management. The aim of emphasizing the whole U+ treatment is to pursue the optimal at each step and go further to reduce the patient’s pain and complications. Laparoscopic gastroduodenal perforation repair should pay more attention to the following matters: 1. Bleeding. Laparoscopic suture of gastric wall tissue, due to edema of gastric wall tissue, or injury of submucosal vascular suture leading to postoperative bleeding, should be closely observed the changes of drainage, color and color of gastrointestinal decompression tube. 2. Infection at the poke card. The contaminated surgical operation of laparoscopic surgery via abdominal wall poke card may contaminate the abdominal wall incision and lead to infection, and the postoperative drug change should be closely observed, and even some patients have poke card hernia. 3, abdominal abscess formation. Due to the large amount of food residue and infected fluid in the abdominal cavity after gastroduodenal perforation, which may accumulate in the right subseptal and left splenic fossa or even the pelvic cavity to form abscesses probably due to poor postoperative activities, postoperative fever of unknown origin and high fever should be alerted to abdominal abscess formation. 4, poor suture healing of gastroduodenal perforation leading to gastroduodenal leakage is a rare complication, postoperative abdominal drainage tube drainage of yellow or yellow-green fluid should be alert, especially unexplained high fever, or unexplained abdominal pain after surgery. Gastroduodenal perforation is mostly gastric ulcer perforation, more prone to perforation recurrence, before the patient is discharged from the hospital should be routinely checked for H. pylori test, if it is positive, H. pylori eradication treatment should be carried out to standardize the treatment. Gastroduodenal perforation repair should be routinely checked by gastroscopy 1 month after gastroduodenal perforation repair to clarify the relevant situation. Because of the risk of re-perforation after gastroduodenal perforation repair, some changes of life details should be carried out: 1, quit smoking and alcohol; 2, avoid eating non-steroidal tired drugs, such as oral aspirin and other drugs must be taken orally omeprazole and other drugs or applied under the guidance of a doctor; 3, avoid staying up late and working overload for a long time; 4, keep a calm mood and avoid factors such as anxiety and tension; 5, eat regularly and live 6.Consult the surgeon or gastroenterologist for H. pylori bacillus monitoring and treatment if necessary. The whole process of the disease, not only focus on preoperative, intraoperative and postoperative, but also the prevention and education of the disease. The promotion of laparoscopic gastroduodenal perforation repair with optimal+ management will improve the efficiency of clinical treatment and bring more benefits to patients.