Psoriasis, commonly known as psoriasis, is a common and recurring chronic inflammatory skin disease. It is clinically divided into four types.
1.Common psoriasis
The lesions start out as light red or red papules or macules with multiple layers of silvery white scales on the surface.
2, Erythrodermic psoriasis.
The whole body skin is diffusely flushed, infiltrated and heavily desquamated. Mostly accompanied by fever and other systemic symptoms.
3.Pustular psoriasis.
On the basis of psoriasis damage, clusters of rice-sized pustules occur, with a flushed base.
4.Arthritic psoriasis.
There are psoriatic lesions accompanied by joint lesions, initially showing significant inflammatory changes, such as redness, swelling and pain, followed by joint bone destruction and joint destruction and deformity.
What is the incidence of psoriasis?
The incidence of psoriasis is about 0.1%-0.3%, and the proportion of men and women is roughly equal. The incidence rate is higher in countries such as Northwest Europe and the United Kingdom and the United States, while the incidence rate in China is about 0.123%, with a higher incidence rate in the north.
What are the causes and pathogenesis of psoriasis?
1, genetic factors: about 15-30% of patients have a family history of morbidity. It belongs to autosomal dominant inheritance, and can also be autosomal recessive inheritance.
2, infection factors: related to bacterial and viral infections.
The onset or recurrence of some patients is related to upper respiratory tract infection or tonsillitis. In children, the onset of pharyngitis and tonsillitis, the skin lesions can be significantly improved after removal of tonsils.
3, endocrine disorders: mainly related to pregnancy, lactation and menstruation. In most cases, the skin lesions are reduced or completely eliminated during pregnancy, and in a few patients, the skin lesions are aggravated around the menstrual period.
4, mental factors: mental tension causes about 14.9%, let’s say, students before and after exams or seafarers encounter wind and waves, due to high mental tension and triggered psoriasis.
5, immune disorders: some patients with psoriasis have low cellular immune function. Patients were found to have anti-keratosis antibodies in their blood.
6.Related to metabolic disorders
4, mental factors: mental tension causes about 14.9%, let’s say, students before and after examinations or when seafarers encounter wind and waves, psoriasis is triggered by high mental tension.
5, immune disorders: some patients with psoriasis have low cellular immune function. Patients were found to have anti-keratin antibodies in their blood
6.Related to metabolic disorders
Pathogenesis of psoriasis
Psoriasis is an immune skin disease with abnormal T-cell function in a polygenic genetic background. abnormal T-cell function leads to secondary epidermal keratin-forming cell proliferation.
Psoriasis is a polygenic genetic and environmental interaction skin disease.
Can psoriasis be inherited?
Psoriasis is a chronic inflammatory skin disease in which polygenic genetic and environmental factors interact.
Environmental factors are an important factor in the development of psoriasis.
According to statistics, one parent with psoriasis has a 40% to 50% risk of psoriasis in their children, while both parents without psoriasis have a 7% risk of psoriasis in their children.
Is psoriasis contagious?
The lesions of psoriasis appear as red patches, papules, and large amounts of silvery white scales, which look dirty and are not contagious to those who are not involved in dermatology.
At present, the medical community has made a lot of experiments: it is proved that there is no bacterial growth in the lesions and scales of psoriasis, but antibodies can be checked. So it is said that psoriasis will not infect others, and I hope that people will not discriminate against psoriasis patients, so that they can keep a good attitude and recover as soon as possible.