H. pylori 440dpm is higher than normal, not serious if there is no stomach disease, but relatively serious if there is gastric ulcer or gastritis. H. pylori 440dpm can only mean that there is H. pylori infection, it does not mean that there is gastric disease, so as long as there is no related disease is generally not serious, you can choose to take oral medication for anti-H. pylori treatment. H. pylori can be cross-infected through diet, so it is recommended to use separate utensils and have family members tested for H. pylori. Anti-H. pylori treatment is usually a combination of four oral medications, mostly proton pump inhibitors (e.g., omeprazole, rabeprazole), two antibiotics (amoxicillin, clarithromycin, and two choices of metronidazole or ornidazole), and gastric mucosal protectants (e.g., colloidal bismuth pectin). The course of medication is 10-14 days, and the medication is followed by a 1-month follow-up. It is recommended to actively seek medical advice and follow the doctor’s instructions for medication and treatment.