Folic acid metabolism low risk generally do not need to take to birth, but also need to be analyzed on a case-by-case basis. Low-risk folate metabolism indicates that folic acid absorption is normal, and folic acid supplementation is generally required during the first 3 months of pregnancy until the third trimester of pregnancy when it is discontinued, and does not need to be taken throughout the entire pregnancy. If the risk of folate metabolism is moderate to high during pregnancy, folic acid supplementation is usually required throughout the entire pregnancy. Proper folic acid supplementation can prevent fetal neural tube malformations from occurring. However, if the pregnant woman has megaloblastic anemia, according to the anemia to correct the situation of reasonable supplementation of folic acid, such as megaloblastic anemia is more serious generally need to be supplemented throughout the pregnancy folic acid and vitamin B12, pay attention to recheck the blood routine situation. In addition to following the doctor’s instructions to take folic acid, but also eat more beef, lamb, animal offal and tomatoes, carrots, cabbage, rape, oranges, pomegranates and other folic acid-rich foods.