The digestion and absorption of fat is mainly by the joint action of bile and pancreatic juice, and bile is not secreted by the gallbladder, so the removal of the gallbladder has no significant effect on fat metabolism. Bile is secreted by liver cells and does not contain digestive enzymes. The most important component of bile is bile salts, whose main physiological function is to bind with fats in the intestines, thus promoting the digestion and absorption of fats. Pancreatic fluid is the most important digestive fluid, containing pancreatic lipase can break down fats and digest them. The main role of the gallbladder is to concentrate bile, and can not secrete bile, after the removal of the gallbladder bile is no longer concentrated directly through the bile ducts into the duodenum to play a physiological role, therefore, after the removal of the gallbladder fat metabolism process and the normal human beings are not significantly different.