Analgesics for bone cancer include the following: 1. weak analgesic drugs, such as non-steroidal anti-inflammatory and analgesic drugs, specifically ibuprofen and fentanyl. 2. strong analgesic drugs, such as morphine controlled-release tablets or extended-release tablets. 3. fentanyl transdermal patch, which can last 72 hours of analgesia after using one dose. Of course, the pain of bone cancer is mainly treated for bone cancer, and the treatment methods include external radiation therapy or particle implantation. Particle implantation has the effect of internal radiation therapy, and zoledronic acid can also be used for anti-bone metastasis treatment. Zoledronic acid is used once a month, which has relatively low side effects and also has the effect of preventing bone metastasis and analgesia. In conclusion, apart from local analgesia, external radiation therapy and topical drugs, the main treatment for bone cancer pain is to deal with the primary cause of bone cancer pain.