Patients with genital herpes can have children, except that primary genital herpes is easily transmitted to the fetus, with a transmission rate of roughly 20%-50%, and can cause fetal miscarriage, premature birth, in utero growth retardation, and even fetal death. In particular, herpes virus infection in pregnant women during the third trimester of pregnancy can cause congenital malformations in the fetus, such as microcephaly, small eyes, abnormal retinal development, brain calcification, and often mental retardation in affected children. Pregnant women with primary genital herpes occurring in the second trimester are approximately 50% more likely to give birth to a baby infected with neonatal herpes virus. However, in cases of recurrent genital herpes during pregnancy, there is generally no effect on the fetus and the risk of neonatal herpes virus infection is less than 8%.