Cholangiocarcinoma is a malignant tumor originating from the extrahepatic bile ducts including the bile ducts from the hilar region to the lower end of the common bile duct. Its etiology may be related to diseases such as bile duct stones and primary sclerosing cholangitis. It can be treated clinically by surgery, radiotherapy, chemotherapy and other methods, but the prognosis is poor. Its symptoms are as follows: 1. Severe jaundice Severe jaundice is a more common and important symptom of early stage of cholangiocarcinoma, and is also the first symptom of many cholangiocarcinoma patients. The cancerous tissues of bile duct cancer often lead to the obstruction of bile ducts and bile duct obstruction, which leads to the inability of bile to flow into the intestine and the backflow into the blood, thus causing the patient’s skin and sclera to gradually turn yellow and brown or bronze, while the stool will turn gray and the urine will turn soy sauce. 2.Indigestion Indigestion is also an important symptom in the early stage of bile duct cancer. In the early stage of bile duct cancer, due to the obstruction of bile duct by cancerous tissues, the digestive juice cannot flow into the intestine, which will seriously affect the patient’s digestive function. 3.Abdominal pain In the early stage of bile duct cancer, patients will often experience serious abdominal pain. Many patients will experience serious abdominal discomfort and often experience pain of dullness, vague pain, boring pain and so on, which also often return to children with rapid heartbeat and serious changes in blood picture. Moreover, the abdominal pain in the early stage of bile duct cancer is often not well localized specifically and the location is vague.