The best time for cervical cancer screening is around the 7th day after menstrual cleansing. Cervical cancer is a common gynecological malignant tumor, usually associated with human papillomavirus infection, and clinically characterized by vaginal bleeding and vaginal discharge, as well as lymph node metastasis. Cervical discharge around the 7th day after menstruation is usually not much, which is more suitable for cervical cancer screening. In the seventy-two hours before the cervical cancer screening, it is best not to wash the vagina and vulva, use medication intravaginally, or have sex to prevent the vaginal environment from being affected, which could affect the results of the screening. Women with family history, early sexual life and multiple sexual partners should undergo regular cervical cancer screening for timely detection, diagnosis and treatment to avoid the spread of cancer affecting women’s health.