Thyroid stimulating hormone is low and high after taking medication can be adjusted under the guidance of the doctor’s medication should be combined with the results of thyroid hormone and other tests for comprehensive assessment. Thyroid stimulating hormone is low, mostly seen in subclinical hyperthyroidism or hyperthyroidism, generally take anti-thyroid drug treatment, such as methimazole, propylthiouracil and so on. Taking too large a dose of antithyroid medication or using it inappropriately may lead to high thyroid stimulating hormone, which can be adjusted under the guidance of a doctor, and should be combined with the results of thyroid hormone tests to comprehensively assess the condition and efficacy of the treatment. Regular review should be conducted during the medication period, and the medication should be adjusted or stopped according to the doctor’s instructions.