For neuropathic toothache, the most effective drug treatment is the use of carbamazepine, gabapentin and other drugs to reduce nerve excitability. Neuropathic toothache is mainly due to neuropathy and high nerve excitability causing toothache symptoms, mainly referring to trigeminal neuralgia, carbamazepine and gabapentin, can be used as the preferred drug treatment for neuropathic pain trigeminal neuralgia. The above drug treatments are generally taken from small doses and keep increasing the dose until the ideal dose, in order to be able to achieve pain relief as the main purpose, while adverse reactions should be avoided. As a maintenance dose can control the pain response, if the effect is not very good, you can choose trigeminal nerve surgery to relieve symptoms, drug therapy must be taken under the doctor’s orders.