White patches of penile skin are mainly caused by localized hypopigmentation or loss of skin pigmentation, and are mostly seen in hypopigmentation spots, senile leukoplakia, vitiligo, etc. 1. Hypopigmented spots: generally due to localized skin hypopigmentation after inflammation, patients often have a history of penile skin infections before, the history of the circumcision glans dermatitis. 2. senile leukoplakia: the main manifestation is the formation of point-like hypopigmentation, can also appear in the penile skin, mostly seen in the elderly group after 50 years old. 3. Vitiligo: Vitiligo is mainly characterized by localized or widespread pigment loss to form white patches, mostly occurring on the backs of the fingers, wrists, forearms, face and other locations, and may also appear in the skin of the genitals. In addition, white patches in the glans may be glans tessellated sclerosis and other inflammatory diseases, in general, white patches of penile skin need to pay attention to, go to the hospital in a timely manner to check, clarify the cause of the disease after targeted treatment.