Toothache and swollen face can be caused by wisdom teeth pericoronitis, apical periodontitis, gingivitis and other diseases, patients can take medication, surgical treatment. 1. Wisdom tooth pericoronitis: For toothache and swelling caused by wisdom tooth pericoronitis, patients can take oral antibiotics such as clindamycin tablets and metronidazole tablets as prescribed by the doctor. Patients can also take surgical treatment, mainly incision and drainage, wisdom tooth extraction, pericoronary gingival flap excision and other surgical methods. 2. Apical periapical inflammation: apical periapical inflammation can also lead to the phenomenon of toothache and face swelling, patients can follow the doctor’s instructions oral ibuprofen extended-release capsules, diclofenac sodium extended-release tablets and other non-steroidal anti-inflammatory drugs, but also oral metronidazole tablets, tinidazole tablets and other antibiotics. Patients also need to undergo surgical treatment, which may include root canal therapy. 3. Gingivitis: For toothache and swelling caused by gingivitis, patients can follow the doctor’s instructions to use compound chlorhexidine gargle, hydrogen peroxide solution and other antibacterial drugs to rinse the gums. Ultrasonic scaling is also needed to remove plaque, calculus and other disease-causing factors from the gum pockets. Patients with symptoms of toothache and swelling of the face may also be caused by pulpitis, caries and other diseases, patients should consult a doctor in a timely manner, and follow the doctor’s instructions for treatment.