The causes of perianal skin rupture in newborns include eczema, allergy, diarrhea, etc., which need to be clearly identified and treated under the guidance of a doctor. 1. Eczema: Eczema in the perianal area can occur after long time use of non-breathable diapers, and in severe cases, the skin will be broken. It is recommended to keep the buttocks dry and clean, use diapers with good breathability, and apply tacrolimus ointment to relieve discomfort if necessary. 2. Allergy: Allergy to diapers or clothing can cause localized allergic reactions resulting in broken skin. It is recommended to change diapers or clothing, and glycerine lotion can also be used to promote symptomatic relief. 3. Diarrhea: prolonged diarrhea will stimulate the anus and cause perianal skin, you can use drugs such as montelukast to relieve diarrhea and promote the improvement of symptoms. Due to the diversity of causes and individual differences, the drug is not absolutely effective and safe, need to follow the doctor’s instructions to standardize the use of adverse reactions in a timely manner to seek medical treatment, drug allergy is prohibited.