Symptoms of unstable urinary microalbumin require prompt medical attention to identify the cause, which may be physiologic or pathologic. Physiological causes do not need to be dealt with or require lifestyle adjustments. Pathologic causes should be under the guidance of the doctor for targeted treatment, such as drug therapy, other treatments. 1. Physiological factors: urinary microalbumin occurs due to strenuous exercise, emotional excitement, diet and so on. Symptoms can be relieved by proper rest, emotional relief and improved diet. 2. Pathological factors: for urinary microalbumin caused by hypertension, angiotensin-converting enzyme inhibitor/angiotensin receptor antagonist drugs such as Benadryl and Valsartan are usually used. Diabetes mellitus, the main control of blood glucose such as insulin; primary glomerular disease caused by the use of glucocorticoids such as prednisone and immunosuppressive drugs such as cyclophosphamide and other drugs according to the condition. When urinary microalbumin occurs, it is recommended to seek medical treatment in the hospital to identify the cause and treat the symptoms under the guidance of the doctor.