Wake up in the morning dry eyes can not open consider is due to lack of sleep, may also be dry eye, conjunctivitis and other diseases caused. 1. Lack of sleep: If the sleep time is too short, or the quality of sleep is poor, the body does not get enough rest, after waking up will appear dry eyes can not open, is a normal situation. 2. Dry eye: dry eye is the discomfort caused by tear film instability and eye surface damage, the etiology is related to insufficient tear secretion, excessive evaporation of tears and abnormal tear composition, etc. Typical manifestations are symptoms such as eye fatigue, foreign body sensation and dryness. 3. Conjunctivitis: Conjunctivitis is a common inflammatory disease that occurs in the conjunctival tissue, the causes of which include infection, immune lesions and external stimuli, etc., the patient will have red, swollen and itchy eyes and other symptoms, which will also lead to dry eyes in the morning and can not open. There are many reasons for dry eyes in the morning, and after eliminating physiological factors, it is recommended that the patient consult a doctor for a clear diagnosis and choose the appropriate treatment.