Headache is one of the most common complaints of neurologists in outpatient, emergency, and consultative settings. This headache is not only numerous, but also miscellaneous. Although most of them are no big deal, give some painkillers and get rid of it. But if you miss a subarachnoid hemorrhage, your career may be over. It’s important to take it seriously. There is a classic saying that a doctor who sees a patient with a headache also has a headache, and a doctor who sees a patient with dizziness also has dizziness. Today we talk about a particularly headache topic: drug overuse headache heard the name you know, is the patient painkillers take too much caused. This is a relatively young disease. The first is fifty or sixty years ago Mayo Clinic several doctors have a stubborn headache patients, every day to take ergotamine painkillers, but still no avail. Instead of abandoning the treatment, the patient was cured. These professors smelled the opportunity to send sci, hurry to collect data collection, the first is a conference speech, his day officially published. Cited countless follow up research. At first they called this headache ergotamine overuse-related headache, then we found that barbiturates seem to eat too much headache, caffeine more pain, simple painkillers will have, review painkillers will also have …… the list is getting longer and longer, a piece of paper will not be able to write the swelling how to do. So in 1988, the research headache experts and professors held a meeting, to this kind of headache named “headache induced by chronic substance use or exposure”, a unified world. Then it slowly transitioned to the name of today’s drug overuse headache. How common is it? The prevalence rate is 1-2%, which means that if you go to the clinic for a whole day, out of 70 or 80 patients, there will be one. These people live what a miserable life? 1, headache is not a disease, the pain is really killing. 2, this drug overuse headache and other chronic headache compared to not only pain, but also more money ah, those painkillers for years to eat up is not cheap. 3, at present, this concept still needs to be further promoted, a lot of people do not know enough, there is an article that these patients, on average, were troubled by primary headache 20.4 years, years with painkillers, can not be stopped 10.3 years, every day with a headache 5.9 years (almost continuous pain ah pro more than 2,000 days), these patients tend to be silently ignored. Here we put together a review of relevant medications. The latest version of the International Classification of Headache (ICHD-3) is divided into the following eight categories: 1, ergotamine 2, Tretinoin 3, simpleanalgesic (simpleanalgesic, usually non-steroidal) 4, opioids 5, compounded analgesic 6, combined medication a (but each individual medication does not exceed the dosage) 7, combined medication b (but the specifics are not known, in fact, and the previous article is a brother, only the last one) Clearly do not overdose individually, this one is not clear about the details) 8, Overuse headache due to other drugs