After discontinuing the use of Eusebio, menstruation will occur in 3-7 days. If Eusebio is used for a long period of time to regulate menstruation or contraception, there is a clinical possibility that the amount of menstruation will gradually decrease. Because the contraceptive mechanism of Eusebio is mainly to inhibit ovulation and change the thickness of the endometrium to make it thinner so that the fertilized egg cannot be laid and achieve the effect of contraception, the menstrual flow may decrease during the oral use of Eusebio. Also, irregular vaginal bleeding may occur while taking Eusebio, and this can be improved by continuing to take it. It is recommended to take Eusebio at a fixed time every day for better efficacy.