Hiccups for more than 4 days in a row are caused by involuntary paroxysmal spasms of the diaphragm and other auxiliary respiratory muscles, and can be seen in diseases such as eating too much too fast, catching a cold, indigestion, gastritis, gastric ulcers, mediastinal tumors, and intracranial pathology; management is often general and pharmacological, including gastrointestinal dynamics, calcium antagonists, and chlorpromazine, among others. 1. General treatment: hiccups can be caused by eating too much too fast, eating too cold, getting cold, etc. You can inhibit spasm of diaphragm and relieve the symptoms by drinking warm water in large gulps, diverting attention, and repeating breathing. 2. Drug treatment: gastrointestinal dysfunction, indigestion can make the air in the stomach accumulation, take drugs to increase gastric power to promote gastric emptying. Commonly used are domperidone, mosapride and so on. Mechanical intestinal obstruction, gastrointestinal bleeding and other diseases are prohibited. Intracranial diseases can often lead to neurogenic eructation, nimodipine, etc. are more commonly used to relax cerebral blood vessels and peripheral vascular smooth muscle. Cerebral edema and increased intracranial pressure are contraindicated. Patients with persistent hiccups may be treated with chlorpromazine if appropriate. Prolonged hiccups may cause negative emotions such as depression and anxiety, and antidepressants may be used as appropriate. 3. Physiotherapy: Hiccups caused by cerebrovascular disease can also be relieved by acupuncture. The above medications should be used under the guidance of a doctor and the specific treatment plan should be carried out under the guidance of a doctor for better treatment of the disease. There are many other reasons for continuous hiccups, it is recommended to go to the hospital, improve the examination, clarify the cause of the disease, targeted treatment.