Plasma and red blood cells are both commonly used blood products in the clinic, they have different components and perform different physiological functions respectively. The order of transfusion of plasma and red blood cells is closely related to the specific condition of the patient, and needs to be decided according to the specific condition of the patient, for example, a patient with severe anemia, accompanied by immune deficiencies, the order of transfusion at this time is the first transfusion of red blood cells, to improve the patient’s symptoms of anemia, to ensure that the patient’s vital signs of the patient is stabilized, and then transfused with plasma. If a patient with obvious coagulation dysfunction leads to bleeding and anemia symptoms, plasma should be transfused first, because the concentration of coagulation factors in the patient’s body will increase after plasma transfusion, and the bleeding symptoms will be improved, and plasma transfusion is followed by transfusion of red blood cells, which can significantly reduce the bleeding symptoms, and at the same time improve the symptoms of anemia. Therefore, the order of plasma and red blood cell transfusion should be decided according to the patient’s condition.