Many older people walk more and more slowly, and feel that their limbs have become stiff, sometimes their arms are bent, they cannot swing freely when walking on one side of their body, or they have hand tremors and other symptoms. In clinical work, neurologists often encounter patients who say that they used to be healthy at work, but after retirement, they walk differently and more slowly. Although patients feel that they are walking slowly, they think that it is due to their age and aging, and do not pay attention to it. Some patients who experience slow walking, sometimes with one leg stiff and dragging, attribute it to overexertion and do not pay attention to it until the condition gets worse. Parkinson’s disease is a progressive neurodegenerative disease of unknown cause, caused by brain dysfunction due to nigrostriatal lesions in the brain. There are four main symptoms: limb tremors; muscle stiffness; slow movements; and abnormal posture and gait. According to incomplete statistics, there are 2 million patients suffering from Parkinson’s disease in China, accounting for about 1% of the total population over 55 years old and 1.7% of the population over 65 years old, with roughly the same ratio of men to women. Parkinson’s disease rarely occurs in people under the age of 40, and the average age of onset is about 60 years. However, in recent years, we have found many younger patients with Parkinson’s disease in our outpatient clinics. The onset of the disease is insidious, with slow progressive development, and the initial manifestations are usually unnoticed by the patient and observed by the patient’s relatives, friends or colleagues. In the early stages of the disease, unilateral limb tremors are observed. When writing, the font becomes smaller and more irregular; fine movements such as buttoning or stirring coffee or milk become difficult; turning over in bed or standing up from a chair appears to be a struggle. Sometimes the patient’s standing posture may be bent forward. The patient may have difficulty starting to walk, and the pace may become small, as if he or she is dragging his or her feet, and then he or she may walk faster and faster, rushing straight ahead. The voice is monotonous, lacking intonation, and the expression is dull, like wearing a mask, called “mask face”. If left untreated, the limbs become stiff and the body balance reflexes deteriorate in severe cases, and eventually the patient becomes immobile and bedridden. In most cases, doctors are able to detect some meaningful clinical signs, and the diagnosis is not difficult for an experienced neurologist.