Sigmoid colon cancer can be treated surgically, and the clinical symptoms can be improved by surgery even in advanced stages. Surgery is the main treatment for this disease, in which early cancers within the mucosa can also be resected endoscopically, and surgical resection is recommended for those with no obvious contraindications (such as severe organ failure, coagulation disorders, etc.). Even for stage IV patients, the 5-year survival rate after radical surgery can reach about 30%, which is significantly higher than the 8% of palliative treatment. If the tumor cannot be completely removed by surgery, obstruction and other comorbidities can be relieved by surgery, or stoma can be performed to improve the quality of life of patients. If the diagnosis of sigmoid colon cancer is confirmed, patients should consult the doctor in time, and choose the appropriate surgical treatment under the doctor’s guidance, and improve the cure rate with postoperative adjuvant radiotherapy and chemotherapy, and the specific treatment plan should be implemented according to the doctor’s instructions.