Probiotics are not significantly harmful to patients with spleen deficiency. Patients with spleen deficiency can take probiotics if they have indications for probiotics. Probiotics mainly refers to intestinal probiotics, taking probiotics can regulate the intestinal flora, so as to play the role of body regulation, prevention of disease, treatment of disease, common probiotics are Bacillus licheniformis live bacterial granules, Clostridium typhimurium bifidum live bacterial powder, bifidobacterium live bacterial powder and so on. Taking probiotics generally will not induce or aggravate spleen deficiency. Spleen deficiency refers to the deficiency of yin and yang, qi and blood of the spleen, and is characterized by emaciation, yellowish color, weakness of limbs, loss of appetite, indigestion of food, abdominal pain, bowel sounds, loose stools (thin and unshaped feces) or diarrhea, and metrorrhagia (excessive menstruation or dribbling), and so on. Patients with spleen deficiency should use probiotics under the guidance of a physician’s interview, and if discomfort occurs during the consumption of probiotics, they should consult a doctor in a timely manner, and patients should not self-medicate.