Changes in the concentration in serum creatinine are determined primarily by the glomerular filtration capacity. If the capacity decreases, the creatinine concentration will increase. Creatinine is an important indicator of kidney function. High creatinine is generally due to the following reasons: I. Kidney infection, patients suffering from renal insufficiency with colds and intestinal infections will have elevated creatinine in the short term. Second, recurrence of kidney disease. Chronic glomerulonephritis, nephrotic syndrome, renal insufficiency, in the treatment is not complete or the infection occurs in the late stage of the prognosis, it will lead to relapse of the disease, and there will be an increase in blood creatinine. Third, drug poisoning. Kidney disease patients take drugs that are harmful to kidneys, creatinine will also rise in a short period of time, in this case, the drugs must be stopped, so that the blood pressure or blood glucose increases, which will also cause high creatinine. Fourth, daily life routine is disturbed, too tired, life details do not pay attention to, can also cause a transient blood creatinine rise.