The main side effects of Compound Digestive Enzyme are vomiting, diarrhea, soft stools, and unpleasant sensation in the mouth. 1. Vomiting: Compound Digestive Enzymes contains pancreatic enzymes, pancreatic lipase degrades fats into glycerol, and divides proteins into peptones and peptides. Some patients taking the drug may produce excessive peptones and glycerol, causing reflexive vomiting. 2. Diarrhea: Compound Digestive Enzyme may cause excessive breakdown of food, resulting in diarrhea. 3. Soft stools: Compound Digestive Enzymes may break down starch into dextrin and sugar, which when broken down too much may cause unformed stools and loose stools. 4. Unpleasant sensation in the mouth: Compound Digestive Enzyme contains Ursodeoxycholic Acid, which can stimulate bile secretion and cause bile reflux, resulting in bitter and dry mouth. It is recommended to take the drug under the guidance of a physician and not to use the drug privately.