Brucellosis, or brucellosis, and whether or not the fever will recur after treatment with rifampicin and doxycycline depends on the patient’s specific situation and cannot be generalized. Brucellosis is an infectious disease of animal origin that is more prevalent in pastoral areas, and patients will have recurrent fever with profuse sweating, and may also have symptoms such as arthralgia, malaise, back pain, myalgia, anorexia, and weight loss. Treatment is usually with a combination of antibiotics, most commonly rifampicin as well as doxycycline. Whether or not the patient will have recurrent fever after taking the medication is related to the severity of the patient’s condition and whether or not he/she is sensitive to the medication, etc. Some patients’ symptoms will be gradually relieved within 10 days of taking the medication, but if the patient’s sensitivity to the medication is low or his/her condition is more serious, he/she may still have recurrent fever and may consider changing the medication. It is recommended that patients follow the doctor’s instructions to standardize the use of medication according to the course of treatment, to observe the therapeutic effect of the drug, and communicate with the doctor in a timely manner.