50 years old forgetfulness and memory loss, the possible causes of physiological factors, pathological factors, such as Parkinson’s disease, Alzheimer’s disease, vascular dementia, etc., need to apply drugs for symptomatic treatment. 1. Physiological factors: when a person reaches the age of 50 and gradually enters middle-age, nerve cells naturally wither away, and memory loss is an inevitable process, with no effective means of treatment. 2. Parkinson’s disease: it is a progressive disease of unknown etiology, some of which will have mild cognitive decline in the late stage, causing amnesia, etc. At this time, Benzhexol hydrochloride, amantadine, levodopa and compound levodopa should be given for treatment. 3. Alzheimer’s disease: including Alzheimer’s disease and vascular dementia, the former memory impairment is the typical first symptom, and near memory impairment is the main, at the same time, cognitive function will also decline; the latter is the cognitive dysfunction caused by cerebrovascular disease, and can be given donepezil, memantine and so on for treatment. The above drugs should be taken in strict accordance with the doctor’s instructions, and should not be taken without authorization or change the dose of drugs, so as not to cause adverse consequences.