Mitral regurgitation does not generally cause an increase in blood pressure, and there is no direct correlation between mitral regurgitation and high blood pressure. The mitral and tricuspid valves are the valves between the atria and the ventricles, and blood regurgitation can lead to increased ventricular volume load, ventricular dilatation, increased ejection burden on the heart, and cardiac insufficiency. Mild regurgitation rarely results in uncomfortable symptoms, but if the condition progresses, the patient may experience chest tightness and shortness of breath. Due to cardiac insufficiency, hypoxia also occurs, but there is no clinical manifestation of hypertension. Hypertension is a clinical syndrome mainly characterized by increased blood pressure in the arterial circulation. Its etiology mainly includes genetic factors, poor dietary habits, drug abuse and so on. Diseases such as diabetes mellitus, sleep apnea hypoventilation syndrome, thyroid disease, renal artery stenosis, renal parenchymal damage, pheochromocytoma, and other neuroendocrine tumors can also lead to secondary hypertension. However, valvular regurgitation is not a direct factor in the development of hypertension. If symptoms related to mitral regurgitation occur, prompt medical attention is required to prevent further aggravation of the condition. At the same time, it is important to pay attention to diet and cultivate good living habits, and monitor blood pressure on a daily basis.