There is a difference between the vagina and the urethra. The vagina is the passageway of the reproductive system, through which the fetus is delivered, and the urethra is the passageway of the urinary system, through which the urine is discharged, which can be understood by consulting a professional doctor. 1. Function: The vagina is the female sex organ and the channel for delivering the fetus, from which the menstruation is also discharged; the urethra is mainly for discharging urine and so on. 2. System: The vagina belongs to the human reproductive system; the urethra belongs to the urinary system. 3. Anatomical location: the vagina is located between the urethra and the rectum; the urethra is located above the female vaginal opening. 4. Secretion: the vagina is often milky white and egg-white secretion outflow, while the urethra is generally not. The difference between the vagina and the urethra mainly lies in the different physiological functions, you can consult the relevant professional doctors or consult the relevant books to understand.