Decubitus ulcers are one of the common clinical conditions, often accompanied by a variety of complications. If patients are delayed or improperly disposed of for a long time during daily care, it may lead to further deterioration of the injury and even cause a variety of other diseases, which may cause a great burden to the patient’s body. 1. Hypoproteinemia Decubitus ulcer patients suffer from decreased appetite, malnutrition and many other factors, resulting in insufficient protein intake or excessive loss, leading to hypoproteinemia. Response: Maintain a balanced dietary nutrition and take more protein supplements to prevent hypoproteinemia. 2.Sepsis Improper care of decubitus ulcers and improper wound disposal lead to infection of the trauma surface, aggravation of local inflammation, proliferation of bacteria on the trauma surface, and continuous invasion of the blood circulation, producing a large amount of toxic substances and causing a series of systemic toxicity symptoms. Response: Timely treatment and regular medication changes, culture testing of traumatic strains, screening of antibiotic infusion for protection, with topical decubitus ointment and other treatment methods to prevent wound infection. 3. Bone infection When decubitus ulcers become serious at a later stage, or when wounds develop deeper, tissue necrosis can spread to bone tissue, causing periostitis and osteomyelitis, which can lead to amputation in serious cases and even endanger life. Response: For deep decubitus ulcers, you should go to a specialist in wound repair and orthopedics in a timely manner, and perform deep debridement of the wound and a certain cycle of antibacterial and anti-inflammatory treatment to eliminate inflammation early and prevent it from spreading downward. 4, cellulitis Wound rupture for a long time does not heal, resulting in Staphylococcus aureus, hemolytic streptococcus or putrefactive bacteria in the skin surface and subcutaneous tissue continued infection, causing severe local pain ulceration, and accompanied by malignant cold, fever and other symptoms, the onset of acute and slow, serious cases can be life-threatening. Response: Early control of wound inflammation is required. In case of persistent swelling and pain, broad-spectrum antibiotics are available for infusion care to eliminate inflammation.