Pepsin can be supplemented by drugs and food. 1. Drugs: after diagnosing low pepsin, patients can supplement polypeptide tablets to replenish the lack of gastrointestinal enzymes, polypeptide tablets generally have no significant adverse effects, but overdose or improper use may cause constipation. 2. Food: you can supplement vitamin B rich food, such as fresh vegetables and fruits, cabbage, apples and pears, etc.; you can eat more acidic food, which can stimulate the gastric glands to be stimulated to increase gastric gland secretion, which can help increase the amount of pepsin. In addition, the lack of pepsin has a certain degree of danger, easy to affect the health, it is necessary to actively accept the treatment, do not be negligent, so as not to delay the condition.