The symptoms of high total bilirubin are jaundice, digestive discomfort, muscle and joint pain, as follows: 1. Jaundice, clinically bilirubin is an important indicator to confirm the diagnosis of jaundice, the destruction of red blood cells release a large amount of bilirubin, not all of which can enter the liver for conversion, stagnation in the blood will lead to jaundice, manifested as sclera, mucus, skin, urine, mucous membranes and other tissues are yellow stained. 2, Discomfort of the digestive system, if the total bilirubin is elevated by liver and biliary disease, there will also be nausea, vomiting, loss of appetite, abdominal pain, diarrhea, weakness of the limbs, and loss of weight, especially after eating fatty foods, the patient’s symptoms will be more obvious. 3. Muscle or joint pain, joint pain and its surrounding muscles will have soreness, usually pain is not intense, often recurring and prolonged The pain is usually not severe, but often recurrent and prolonged.