Hand eczema should be treated according to the period of the disease, and glucocorticoid creams, boric acid solutions, antibiotics, etc. can be used. Eczema is an inflammation of the superficial dermis and epidermis caused by a variety of internal and external factors, and the course of the disease can be divided into acute, subacute and chronic phases. Acute stage lesions are mainly dominated by herpes mound, glucocorticoid creams such as prednisone, methylprednisolone, etc., but also boric acid solution or isacridine solution, with disinfection, anti-inflammatory, astringent effect, but also can be used alternately with oil. Glucocorticoid emulsions and pastes can be used in the subacute stage, and antibiotics can also be added to prevent and control secondary infections. Chronic period is mainly mossy, can choose ointment, hard, film coating agent, stubborn limited lesions can use glucocorticoid local sealing. Hand eczema should be timely consultation, under the guidance of the doctor for treatment, daily attention to hand hygiene, pay attention to rest.