When doing chest CT examination, it is suggested that obvious enlarged lymph nodes are seen in the hilum and mediastinum, first of all, it should be considered whether it is caused by inflammation or metastatic lymph node enlargement of tumor, and there is a possibility of lymphoma, which needs to be treated according to the cause of the disease. 1. Lymph node enlargement caused by inflammation: pneumonia, upper respiratory tract infection, pleurisy and other diseases can cause reactive enlargement of lymph nodes in the thorax, which can be treated by treating the primary disease, applying antibiotic therapy such as cephalosporin and penicillin, and choosing appropriate antibiotic therapy according to the drug sensitivity culture, and the enlarged lymph nodes will be reduced after treatment. 2. Metastatic lymph node enlargement: if the tumor has metastatic lymph node enlargement, it is necessary to further improve the examination to find the primary foci and make clear whether there is distant metastasis, and then formulate a comprehensive treatment plan according to the examination results, such as no distant metastasis and feasible surgical treatment, such as the primary foci is too large to be resected, and feasible radiotherapy, immunotherapy, targeted therapy, and other comprehensive treatments. 3. Lymphoma: it is malignant tumor of systemic lymphatic system, which can occur in lymph nodes in any position of the whole body and cause lymph node enlargement, and once diagnosed, it needs to be treated with radiotherapy and chemotherapy in time. Therefore, after chest CT examination reveals obvious enlarged lymph nodes in the hilum and mediastinum, you should go to regular hospitals to find professional doctors to judge and clarify the cause of the disease, so as to avoid delaying the disease.