Differential pressure greater than 70mmHg should go to the hospital in time to find out the cause of the disease and then symptomatic treatment. Normal pulse pressure difference is between 30~40mmHg, if the pulse pressure difference appears to shrink or increase, it means that the body has an abnormal state, generally vascular atherosclerosis caused by systolic blood pressure increase, will cause the pulse pressure difference to increase significantly. Differential pressure greater than 70mmHg need to be under the guidance of the doctor through oral antihypertensive drugs to regulate, such as nifedipine extended-release tablets and enalapril and other drugs, taking drugs during the period of need for regular measurement of blood pressure. In addition to atherosclerosis, it may also be caused by hyperthyroidism, aortic insufficiency and other factors, so it is recommended to go to the hospital as soon as possible for thyroid, cardiac ultrasound and other related examinations to clarify the cause of the disease.