The difference between imatinib tablets and capsules is that the dosage form is different and there is not much difference in the efficacy. Imatinib, also known as imatinib mesylate, is used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia in the chronic phase, unresectable or metastatic malignant gastrointestinal mesenchymal stromal tumors (GIST), and is available in two dosage forms: tablets and capsules. Imatinib tablets and capsules are actually more or less the same in terms of drug effects, except for the different dosage forms, which are mainly chosen according to the patient’s situation, needs and so on, to see which one is more suitable. Patients may experience adverse reactions such as edema, nausea, fatigue, fever, etc., which need to be properly monitored, and at the same time, it is forbidden for those who are allergic to the drug-related active substances or any excipient components, so the drug needs to be taken under the guidance of a professional doctor or clinical pharmacist.