The following causes predispose to hyperthyroidism: i. Autoimmune factors. Patients with hyperthyroidism and autoimmune thyroiditis belong to the same category of autoimmune thyroid disease. Family members of hyperthyroidism patients are more likely than others to develop anti-thyroid autoantibodies and chronic autoimmune thyroiditis. Genetic factors, hyperthyroidism has a significant genetic predisposition, and the risk of siblings developing the disease is 11.6%. The incidence of thyroid abnormalities in children of hyperthyroid patients is twice as high as that of children of non-hyperthyroid patients. Environmental factors such as bacterial infection, stress, smoking, iodine intake, etc. Smoking increases the risk of developing hyperthyroidism by 1.5-2 times, and stress factors such as divorce, loss of love, unemployment and other unfortunate events can easily cause hyperthyroidism.