Many mothers are extraordinarily concerned about girls who develop during puberty. In our work we see some cases of visits for asymmetrical labia minora development, which is unilateral hypertrophy of the labia minora and is not a serious developmental abnormality and in most cases there are no symptoms or discomfort. Some patients may have symptoms of vulvar irritation, chronic infection, pain, or activities that interfere with the compression of the vulva, such as horseback riding. For those who have these symptoms of labial hypertrophy, they should pay attention to local vulvar hygiene and avoid wearing tight clothing. If symptoms persist or if they wish to improve the appearance of the abnormality, the overly enlarged part of the labial tissue can be surgically removed to form symmetrical, appropriately sized labia. However, whether it is a simple unilateral hypertrophy of the labia minora, a gynecological examination and developmental evaluation should be performed at a specialized hospital.