Sweat herpes can be treated with topical glucocorticoid medications and oral antihistamines, but the disease is a chronic recurrent condition with no method of eradication. Herpes perspiration, also known as dyshidrotic eczema, is a blistering skin disease that occurs primarily on the palms and metatarsals. Herpes perspiration has a chronic course and can be treated with topical glucocorticoid medications, such as halometasone ointment, compounded flumethasone ointment, or calcineurin phosphatase inhibitors, such as tacrolimus. Combined with antihistamines, such as loratadine and other drugs for treatment. Daily need to avoid contact with allergens, irritants, avoid repeated contact with detergents, disinfectants. Daily need to keep hands clean and dry, avoid scratching stimulation. Specific medication should be used in accordance with the doctor’s instructions.