What is interventional therapy for liver cancer? Among the treatments for liver cancer, interventional therapy is one of the more common ones, so do you know what are the side effects of interventional therapy for liver cancer, what is interventional surgery for liver cancer, and what is the post-interventional care for liver cancer, let’s learn more about it together. Interventional therapy is different from simple chemotherapy, which is unnecessary for 3-4 weeks and can be done 3 to 4 times in case of very good efficacy. However, pure interventional therapy can not kill liver cancer cells completely, even the most successful interventional surgery, biopsy in the original part can still be found in the cancer cells, so it is easy to recur and metastasize after interventional therapy for liver cancer. Moreover, there are certain toxic side effects. Interventional drugs stimulate nerves, which will cause pain, and damage to immune system will cause fever. I. Side effects of interventional therapy for hepatocellular carcinoma 1. Impairment of liver function Impairment of liver function is the main side effect of interventional therapy for hepatocellular carcinoma, mainly manifested as elevation of alanine aminotransferase (ALT), with an incidence rate of 7% to 100%, which is mostly due to the cytotoxicity of chemotherapeutic drugs, embolizing agents and absorption of necrotic tissues after treatment. Gastrointestinal reaction The incidence of gastrointestinal reaction is as high as 44.8%～83%, mostly due to the digestive reaction caused by the interventional drugs, which is manifested as nausea, vomiting, decreased appetite or lack of appetite, and so on. 3.Decrease in blood image The incidence of leukocytes decreased from 30% to 25%, mainly due to the bone marrow inhibition of chemotherapy drugs, which usually occurs 2 weeks after the operation. 4, pain, mainly in the upper abdomen, the incidence rate of 3O% l00%, mostly due to local ischemia of the liver after embolization, resulting in local swelling of the liver blood vessels to stimulate the hepatic peritoneum, or contrast medium, embolization agent caused by direct stimulation, usually occurring in the first 24 hours after the operation. 5. Fever The incidence of fever varies from 10% to 100%, which is mostly caused by acute ischemia, necrosis, detachment and absorption of tumor tissues. Generally, it occurs on the 2nd day after interventional therapy for hepatocellular carcinoma, and the temperature is between 37.5-38℃, which can last for 5-7 days, but there are some individual patients with body temperature above 38.5℃, which lasts for 9 to 14 days. Injury of puncture site The incidence is between 2% and 13%, which is manifested as local bleeding, hematoma, spasm of arterial and venous veins or thrombosis, etc. It is mostly due to the obstacle of patients’ coagulation mechanism, intraoperative application of heparin or postoperative hemostatic compression excessively, and so on. In hepatocellular carcinoma, vascular intervention is the most widely used category in the treatment of hepatocellular carcinoma. Selective hepatic artery embolization, selective hepatic artery embolization, selective hepatic artery embolization. Its main physiologic basis is normal hepatocytes in the hepatic artery, 25% to 75% in the hepatic artery and 85% to 20% in the portal vein. The blood supply of 90%～95% of primary liver cancer provides anatomical basis for vascular intervention for liver cancer. The specific technical method is the same for all three, which is to puncture a small opening of roughly 3-5mm in the skin, cannulate from the intra-arterial to the blood supplying artery of hepatocellular carcinoma, and then administer the drug through the catheter, with the difference in the drug given. Selective hepatic arterial infusion TAI therapy involves intra-arterial infusion of a drug through a catheter at a dose equal to or less than that given intravenously. This increases the local drug concentration in the target cells and prolongs the contact time between the drug and the lesion, and reduces the total systemic dose of the drug to improve efficacy and reduce side effects. The efficacy of chemotherapeutic drugs is positively correlated with the effective blood concentration of the drugs in the tumor site and the contact time between the drugs and the tumor. In addition, it can also be infused with Chinese medicinal preparations and CIK cell relay immunotherapy. Selective hepatic artery embolization (TAE) is to selectively inject the embolic agent into the tumor blood vessels and arteries supplying blood to the tumor through a catheter, blocking the blood supply to the tumor and sealing the tumor vascular bed, so as to inhibit the growth of the tumor. This is equivalent to “starving” the tumor to death. Commonly used embolic agents include gelatin sponge, super liquefied iodine oil, sodium alginate microspheres and so on. Selective hepatic artery chemoembolization (TACE) is to give both chemotherapeutic drugs and embolic agent through catheter. Tumors are eliminated through both pathways. Tumor Typing Comprehensive Treatment SystemTumor Typing Comprehensive Treatment is the planned and rational application of existing treatment means according to the patient’s organic condition, pathological type of tumor, invasion range and development trend, in order to maximize the cure rate and improve the quality of survival. It is a new type of program for treating tumors at the present stage, and it is the basic principle for the treatment of the vast majority of tumors at present.