The two plus signs of occult blood in men’s routine urine test need to be treated, but you need to go to the hospital for examination to clarify the cause of the occult blood before the right treatment. There are many causes of occult blood with two plus signs, and the treatment varies from cause to cause. If there is a trauma to the lower back or lower abdomen, resulting in a contusion of the kidney and bladder, two plus signs of occult blood may occur. In this case, bed rest or avoiding excessive activity is required, and the occult blood may disappear after recovery, but if the trauma is more serious, hospitalization is required. Infection can also cause occult blood with two plus signs, after examination and diagnosis, oral anti-infective drugs are needed, after the inflammation is cured, the occult blood can return to normal. When there are stones in the urinary system, such as kidney stones or ureteral stones, two plus occult blood can occur. If the site of the stone is diagnosed, extracorporeal shock wave lithotripsy, medication or surgery is required to achieve a cure. In the case of elderly men, it is also necessary to consider that there may be a tumor in the urinary tract causing occult blood, which requires hospitalization and surgery after the examination and diagnosis to cure. Therefore, it is necessary to choose different treatment methods according to different causes.