Adenosylcobalamin tablets generally do not cause cardiac discomfort adverse reactions, if the cardiac discomfort due to adenosylcobalamin tablets, can be discontinued under the guidance of a physician; if not because of adenosylcobalamin tablets cardiac discomfort, according to the specific cause of the disease for treatment. 1. Cardiac discomfort caused by adenosylcobalamin tablets: adenosylcobalamin tablets are vitamins, mainly used for megaloblastic anemia, dystrophic anemia, anemia in pregnancy, polyneuritis, radiculitis, trigeminal neuralgia, etc. At present, there is no research data indicating that the drug can cause cardiac discomfort, if there are no symptoms before the drug is not taken, but after the drug appears symptoms, then consider discontinuing the drug. 2. Cardiac discomfort not caused by adenosylcobalamin tablets: there are cardiac discomfort symptoms before taking adenosylcobalamin tablets, because long-term anemia may cause myocardial ischemia, hypoxia, which can cause discomfort symptoms, consider the symptoms caused by anemia, still need to continue to take the drug, after the anemia improves, cardiac symptoms can be improved. Other diseases that cause cardiac discomfort while taking adenosylcobalamin tablets include coronary heart disease, which requires the use of antiplatelet drugs such as aspirin and clopidogrel, and lipid-lowering drugs such as Rosuvastatin and pitavastatin. There are also hyperthyroidism, hypothyroidism, arrhythmia, etc. which can cause cardiac discomfort. If cardiac discomfort occurs during the taking of drugs, it is recommended to consult a doctor in a timely manner, under the guidance of a physician to clarify the cause of the disease, do not stop the drug or treatment without authorization, to avoid adverse consequences.