Temozolomide is mainly used to treat glioblastoma multiforme or mesenchymal astrocytoma, among others. Side effects include constipation, anorexia diarrhea, rash, and fever. Temozolomide is mainly used for the treatment of glioblastoma multiforme or mesenchymal astrocytoma, including recurrent or progressive glioblastoma multiforme or mesenchymal astrocytoma, newly diagnosed glioblastoma multiforme, and so on. Temozolomide’s adverse reactions are mainly (partially): 1. infections: common oral candida, herpes simplex virus, and wound infections; 2. blood and order lymphatic system: white blood cells, lymphocytes, thrombocytopenia, etc; 3. endocrine and metabolic: Cushing’s-like syndrome; 4. nutrition and metabolism: loss of appetite, hyperglycemia, hypokalemia, etc; 5. mental: anxiety, agitation, etc; 6. neurological: headache, dizziness, aphasia, balance disorders 7. visual and auditory: blurred vision, hearing impairment, etc; 8. digestive system: constipation, nausea, vomiting, etc; 9. skin: hair loss, rash, etc. It is recommended to use medication under the guidance of doctors in regular hospitals, do not use medication on your own, and consult a doctor promptly if you feel unwell.