Stomach discomfort after waking up in the morning is mostly caused by diseases such as gastric ulcer and chronic gastroenteritis. Since the intestines are relatively empty in the morning after a night of digestion, gastric juices as well as secretions in the intestines can come into direct contact with the intestinal mucosa. If you suffer from intestinal or gastric ulcer, the contact of gastric juice with the ulcer may cause pain, heartburn, nausea, vomiting, etc., which will disappear after eating breakfast. If there is no medical intervention for a long time, gastric ulcer or gastroenteritis may be transformed into gastric bleeding or even gastric cancer, so it is important to be alert when there is long-term stomach discomfort in the morning. It is recommended to go to the hospital for gastroenteroscopy and take appropriate drugs such as thioglycollate suspension and cisapride to protect the gastric mucosa, and follow the doctor’s advice for the specific treatment plan.