Targeted drug resistance means that the drug can not function normally, and will not cause damage to the body leading to death, patients can be under the guidance of the doctor to change the drug treatment or radiotherapy to control the disease. The emergence of drug resistance to targeted drugs means that the body’s absorption and metabolism of the drugs during the taking of targeted drugs are abnormal, causing a decrease in the efficacy of the drugs or even the inability to play a normal pharmacological effect. After the emergence of drug resistance, it is recommended that the patient should consult a doctor in time, and change the targeted drugs or radiotherapy after the doctor’s professional assessment, common targeted drugs include bevacizumab, trastuzumab, etc., and common chemotherapy drugs include paclitaxel, cisplatin, etc.. You need to choose under the guidance of the doctor in combination with their own situation, the emergence of adverse reactions to timely consultation, drug allergy is prohibited. After the emergence of drug resistance after active treatment can effectively control the development of the disease, improve the quality of survival, prolong the survival time, will not die soon.