Gastric pain accompanied by bubbling sounds from the stomach is considered to be caused by gastrointestinal diseases such as gastric ulcers, eating irritating foods, or psycho-emotional factors. 1. Gastrointestinal diseases: usually the main cause of this symptom, when the patient has gastric ulcer or duodenal ulcer, gastroenteritis and other underlying diseases, due to the air in the stomach and peristalsis produced by the contraction of gastrointestinal smooth muscle, resulting in the emergence of the bubbling sound and pain sensation. 2. When eating unclean or irritating food, it triggers the smooth muscle of gastrointestinal tract to contract violently or even spasm, thus causing the bubbling sound and pain. 3. When the patient is in a bad mood, it is easy for indigestion to occur, resulting in accumulation of food, causing gastrointestinal tract dysfunction and bacterial flora imbalance, which can lead to the bubble sound and pain. In short, we should first consult a doctor for a clear diagnosis, and then adjust the work and rest to restore a good mood, if necessary, under the guidance of the doctor to take drugs such as montelukast, domperidone and other medications for treatment.