Cotrimoxazole and Montelukast can generally be taken at the same time, and both of them can effectively control the symptoms of cough, sputum and wheezing caused by asthma. 1. Cotrimoxazole: The ingredients include Methoxynamine Hydrochloride, Chlorpheniramine Maleate, Aminophylline, etc. It has the effect of calming asthma and relieving cough, and is effective for bronchial asthma and respiratory symptoms caused by coughing, coughing up phlegm and wheezing. The drug may cause symptoms such as rash and nausea and vomiting, and is contraindicated in breastfeeding, children under 8 years of age, and patients with asthma crisis. 2. Montelukast: belonging to the leukotriene receptor antagonist, it is effective for the prevention and long-term treatment of asthma in adults, but should not be used to treat acute attacks of asthma, and can be used to alleviate the symptoms of allergic rhinitis. The drug is generally recommended to be taken at night before bedtime. The product is generally well tolerated with mild adverse effects. It is contraindicated in people who are allergic to the ingredients of this product. Both drugs, Cotrimoxazole and Montelukast, need to be regulated under medical supervision and need to be used in strict compliance with the doctor’s instructions.