How long does it take for acne to disappear with Adapalene Gel is not clear in the clinic, usually the symptoms start to improve 4~8 weeks after use, and the symptoms can be significantly improved after 3 months. Adapalene Gel has anti-inflammatory effect, mainly used for the skin treatment of normal acne with papules, pimples and pustules as the main manifestation, but also can be used to treat acne on the chest, back and face. Symptoms of acne begin to improve 4 to 8 weeks after the use of Adapalene Gel, while symptoms can improve significantly after 3 months. It is important to note that Adapalene Gel is contraindicated in people who are allergic to Adapalene Gel, and Adapalene Gel should not be used in patients with very severe acne, nor should it be used on eczema-like skin wounds or skin breakouts. Moreover, adverse reactions such as erythema, scaling, dryness, itching, uncomfortable burning and tingling of the skin may occur after using Adapalene Gel. If you want to use Adapalene Gel, it is recommended to use it under the guidance of a doctor, do not use it on your own, so as to avoid improper use of medication and delay the condition.