Patients with SLE can generally have sex, but they need to pay attention to the frequency and timing of sex. Since SLE generally does not affect the sexual function of patients, patients can not only get married, but also have sex. Since the normal immune function of the body of SLE patients is weakened, coupled with the need to take hormones, immunosuppressants and other drugs orally for a long time, there are problems such as weaker constitution, poor resistance and susceptibility to pathogenic microorganisms. Therefore, in terms of sexual life, SLE patients especially need to pay attention to personal hygiene to avoid and reduce the possibility of gynecological or urinary tract infections. For patients in the acute or active stage of the disease, they should refrain from sexual life or reduce the frequency of sexual life as much as possible to reduce the body burden and prevent further aggravation of the disease. In addition, since pregnancy and childbirth are dangerous for SLE patients when the disease is not in complete remission, and abortion and induction of labor are also dangerous, and oral contraceptives are also a negative impact on lupus, and immunosuppressants for lupus have the risk of causing fetal malformation, good contraceptive measures need to be taken during sex to avoid unintended pregnancy as much as possible. Therefore, SLE patients can have sex, but it is recommended to do it as much as possible during the remission period, not too often, pay attention to personal hygiene, and take good contraceptive measures at the same time.