Patients with medial collateral ligament sprains should first be given emergency treatment, and then can be treated through conservative treatment or surgery and other methods of targeted treatment. 1. Emergency treatment: patients with medial collateral ligament sprain in acute injury, should immediately rest and brake, elevate the affected limb, within 72 hours to take the way of ice to relieve pain and reduce swelling. 2. Conservative treatment: If the ligament sprain is mild, conservative treatment can be carried out, given a plaster or brace fixation, braking of the knee joint, bed rest, you can follow the doctor’s instructions for oral acetaminophen tablets, ibuprofen extended-release capsules, diclofenac sodium extended-release tablets of non-steroidal anti-inflammatory drugs such as pain relief, 6-8 weeks according to the recovery of the situation of gradual weight-bearing exercise on the ground. 3. Surgery: patients with severe sprains of the medial collateral ligament, even ligament rupture, should take surgical treatment, should wear a brace after surgery, under the guidance of the doctor for rehabilitation training. Patients with medial collateral ligament sprains should actively cooperate with doctors and take treatment measures to avoid aggravating the condition.